Yes, I'd say Lantus might affect my daughter more than Novolog as far as weight gain. She was on Lantus & Novolog pens initially, put on weight, then tried the pump, weight stabilized, then went back to pens & Lantus & she's put on a few more pounds. We battle her constant hunger. She takes 30 Lantus at night. Her weight is fine, but I wonder about the cycle of insulin/hunger/weight. It seems like we're missing some trick? But there's no way around it?? Hungry/Eat/Insulin/Hungry...and exercise doesn't affect the hunger, although it helps with blood sugar.