@jjm335 , I hope you won't take my disagreement below with the points you are making negatively!
From an experimental point of view this seems suboptimal to me. The reason for the 2 samples, I am guessing, is that the measurement from a meter-strip system is very noisy (i.e. inaccurate), by often 15% or more: the multiple measurements allow you to take out some of that noise. So making sure to get 2 different drops of blood, possibly from different hands, at a slightly different time even, makes more sense to me. Since a strip/meter measurement can be very far off, it makes sense that you would like to dial out some of the measurement noise as well as possible.
My understanding is that CGMs work best in the ranges that you calibrate them for. And - meter/strip systems' accuracy is much worse when high or low than in the 80-120 range, where they are best. So I see two problems with calibrating high or low:
1. you are getting the worst possible accuracy from the meter/strip system to measure from
2. you are calibrating for a range where accuracy is less important to you.
If you read the Ponder book Sugar Surfing, btw, he spends a whole chapter on the need to calibrate well, and discusses specifically the reasons why you don't want to calibrate high or low, but, instead, in-range.
Of course, as usual for diabetes practices, we should all be ready to go our own ways. But I think it is useful to discuss pros and cons so that everyone can make an informed opinion!