I've been a Type 1 diabetic for /years/ (25+) and started on Human insulin.
In chatting with Richard (who is a pillar in the diabetic community) I learned that animal (and real human insulin) contains 2 proteins and not just the one - and that the RDNA insulin I started on and almost all of us are now on - lack C-Peptide.
Richard and other "long term survivors" have commented how tough the transition was - and that the new RDNA insulins had a phenomena known as "hard to perceive lows."
Further research I have conducted suggests that as many as 10% of our fellow Type 1s have this "very hard time" with the new RDNA insulins, and that there has been a bemoaning to return to some form of the Animal insulins with the C-Peptide.
I noticed that Wockhardt actually still make Pork, and believe it or not - Porcupine insulins - animal based, C-Peptide included.
Now here's the rub - in the US - it appears big pharma are "keeping it out" - they have all but abandoned animal insulins for the far more profitable "synthetic" ones.
However - I have discovered it is possible to get these - directly from the manufacturer. There are a few steps, essentially you need a permission letter from the USDA ($94 fee for 5 years) and a letter from your doc saying you do better on animal insulin, and a letter committing that the insulin shipped to you is strictly for personal use.
Has anyone here in the US gone through this process?
I'm actually curious because i'd actually be interested in determining the differences in my personal health using animal based (C-Peptide included) insulins versus the faster, cheaper to make, better profit margin for the manufacturer insulins.
Can anyone comment whom have gone through the process?
Has it made a difference?
Here is the process if anyone is interested in obtaining direct access to animal based insulins.
Note: I am a Type 1 diabetic, computer geek, and just plain curious.