Thanks Aeon for bringing this old post back to the surface. I would love to see a better designed study of tight control in T2. One that emphasizes a moderate low carb diet and exercise without the harmful drugs such as Avandia and the likes.
I would like to see a study where insulin is used more frequently when the drugs without cardio risk do not do the job. Then maybe we will see progress in the treatment of T2. It's my opinion that the 2 and 3 drug combos frequently seen in T2 treatment is a dangerous approach that frequently does not work.
It's no wonder the ACCORD study did more damage than good in the hard to control group considering the cocktail of drugs given to them. Recent interpretations of ACCORD just goes to prove this point.