Afrezza An Ultra Rapid-Acting Insulin / Inhaled Insulin Onset 12 minutes!!!!
I have been on Afrezza now for months. It is an ultra rapid insulin that is inhaled. I been on it now for 4 months and it has changed my life as I have no more worries of nighttime lows or lows throughout the day. When I was on Humolog / Novolog / Humilin my lows were daily. As we know this is a killer among diabetics as 1 in 20 will die from a low blood sugar.
Last year I almost went into coma 2 times and barely got revived the 2nd time. I also have had numerous lows rushing to the fridge on Novolog and Humolog. This all changed 4 months ago. I have been needle free for 4 months other than taking my daily Lantus. I have had 0 severe lows and only a few lows under 70 in 4 months. I have no daily swings over 250 readings anymore.. Why is this? It is because my management with Afrezza is so easy when I can adjust my blood sugar in minutes. Afrezza is about 90% out of my system in 30-40 minutes after taking it. So lets say I eat a late meal at 10pm. I can take my insulin and at 11pm before going to bed if my sugar is good I know its impossible for me to have a low at night. This has freed from all the stress and scares of lows.
Not only has it effected me this way but all my family members have noticed that I never have any emergencies or rushes for sugar..They all are able to sleep well with no worried about me during the night.
So why am I saying all this?
It actually makes me ill knowing that most people do not even know that this is coming and should of been available to all diabetics already. People die every day of low blood sugar. How about kids that have to damage this disease and the parents who are worried sick every night. I am not even sure how they can sleep. The inhaler is the size of my pinky as the pictures shows. I can have it in my pocket wherever I go and take the insulin anytime anywhere. The insulin is in powder form in the little cartridges.
For me controlling diabetes is now in real time as I dont have to wait 1-2 hours for it to start working and lingering on for 4-5 hours. If my blood sugar is 300 and I can adjust to 100 in 25 minutes. It is truly amazing and if anyone is reading this and has experienced lows please free to ask questions.
Tags: afrezza, blood, control, dangers, hypoglycemia, inhaled, insulin, low, of, on, More…
Replies to This Discussion
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Permalink Reply by AfrezzaUser on -
Exubera offered no clinical benefit. It was the size of tennis ball can. You probably did not know that many Exubera patients received compassion use permit by the FDA and have been on Afrezza for 5 years after Exubera went off the market. Exubera offered no benefit other than the fact that it was inhaled.
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Permalink Reply by Timothy on -
I only brought up the exhubera study because of the issues with dosing. The afrezza has the same issues. If my sugar is 160mg/dl I need about 1.5 units to bring me into range 90-120. if I took 5 units, it would crash me, so I'm left at 160. often I will take just 1 unit to correct. Most meals are 4 units for me. How could I manage such large doses? You never address that issue. also the issue of coughing.
I am glad it works for you, But I can not figure how this could work for me.
You keep saying that you don't crash, but if I took its' lowest dose, I would crash for sure in almost every possibility. Only If I am eating and already high could it work.i could never get past this with exhubera and I can not see this being different. and of course you didnt address the fact that you are not permitted to talk about a drug when the study is still active.
All these reasons make me doubt what you are saying.And it was never as big as a tennis ball can, about half that, and that has nothing to do with its efficacy.
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Permalink Reply by AfrezzaUser on
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Sorry for the blunt response but Exhubera has nothing to do with Afrezza. I have the best A1Cs in 10 years at this moment. The only think Exhubera have in common with Afrezza is that it is inhaled. As far as your worry about violations.. My study is an open label study...I know exactly what I signed...I appreciate your concern.
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Permalink Reply by AfrezzaUser on
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No all type 1s and type 2s on the study are taking Afrezza only and lantus as the basal. Once again everyone here is trying to compare apples and oranges as far as the units of insulin. The best example I can think of is asking your friend how much he paid to fill up his gas tank...He tells you $100 and you say how could that be I only paid $30....Well your friend has a Hummer and you have Nissan Sentra. What I am saying 1 unit of Afrezza is not 1 unit of Humolog. Just because its called a certain unit is not relevant as over 5000 patients have started Afrezza with the smallest dose available. If the smallest unit cart would be too much why did the FDA ask for trials as young as 4 years olds. You make some great points about fast correctins. I can for example bring my sugar from 250 to 100 in 25 minutes. This is huge for bedtime...I can tell you that you will never catch me taking humolog or novolog no matter how high my sugar is after 9 or 10pm. No such issues now for me.
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Permalink Reply by Equestrian on -
I would like to know if you own the stock. Thank you
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Permalink Reply by JohnG on -
I think many are missing the point, this forum is for the most part people that are over achievers, people that are OCD about their BG, Afrezza is not for most of us we are looking for best, not easy.
My brother would be a good candidate for Afrezza, he only has a interest in getting his BG lower if there is some kind of drama involved, he only checks his BG when he is shaking like a Chiwawa or sweating like a pig. He would like it even better if it was mixed with his Rogaine (Minoxidil)...his vanity is far more important than his BG.
This stuff is great..Directions...just inhale this before each meal...and chow down ...it's a dream come true....it sounds like a recreational drug.
It took a family intervention to get my brother to start insulin. 11 years of A1c's between 8.0 and 11.0 never phased him and he said his doctors are stupid...[I feel fine I'm just not ready yet] My brother is a T2 and I'm a T1 we have little in common my trip started at the ER and was like getting beat with a baseball bat..."I got the message the first time"..no one had to sale me on the idea of using insulin.
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Permalink Reply by Josephine A Ni Dhomhnaill on -
It sounds too good to be true, maybe if it can dose for tiny amounts of insulin. At the moment I'm rarely taking over 2-3 units. This could all change next week. I'd much prefer to take my shots so I know what I'm getting exactly. Hopefully it will work for some people. Don't snack or eat late either. Don't eat an awful lot at all, come to think of it I may just go mad altogether and smoke the insulin, try anything once.
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Permalink Reply by tebbemae on -
Thanks for sharing! Just wondering-what will you do when the clinical trial is over? Will you go back to novolog/humolog? Are you allowed to share how this impacted your physical health? If so, have you noticed any changes in breathing since beginning afrezza? Unfortunately I was an idiot in college who smoked cigarettes recreationally (disgusting, I know), would my past history-over 10 years ago-of smoking preclude me from afrezza? I am a pumper and do have many swings (mostly do to absorption issues) but I am also a low carber (never more than 12 a meal). Do you think afrezza, if approved, would try and develop a smaller cartridge? I will definitely check the link to the website. For me, any kind of diabetes innovation is warmly received!
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Permalink Reply by AfrezzaUser on
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Sorry for the late response. The FDA has asked trials for as young as 4 year old children. This was the FDA when in fact the company wanted 10+ year olds...Fda came back and said no start at 4.....Yes its an open label study I can share whatever I want to..For the trials you could not be a smoker..In previous trials you could be a smoker. No change whatsoever....My health was already great and now much better. As a diabetic my biggest concerns is the swings...I have no such issues anymore. I am very active person and now I do not have to worry about lows while swimming, running, biking and so on. It has really changed my life. I wanted to share this with others who have had similar issues and it seems half the people attack you ...lol...You kind of wonder why..Not every treatment is for everyone. For example I dont have a pump. I dont want one. Do I attack people that use pumps? Its ridiculous. As far as what will I do have the trial is over? Well I can tell you no way I am going back on Novolog or Humolog. FDA has opened the door for people like myself. I will update you on this soon. Just keep this in mind...The big deal is not that it is inhaled...Everyone misses the point. The big deal is it works just like your pancrese...THe onset is almost the same as if your pancrese is releasing the insulin and is out of your system 25-40 minutes...It is so easy to manage this as i can correct my blood sugar from any level in a matter of 25 minutes or so. Also no more fear of the night.. Will I wake up. Once you had the paramadics bring you back ...you know how that is..Hard to forget. I congratulate all those people who have A1C levels in the 5s and 6s...Well most diabetics in the USA do not have such control. If someone has A1Cs in the 5s as a type 1 without ever going low it is hard to believe but still if one does stay with your program. If you are a diabetic that have had many lows and issues with swings Afrezza will def....be a potential life saver....
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Permalink Reply by Don on -
Tx. Going to suck for you to go back to needles in the time between the end of your trial and when is available for sale!
Surely you still get lows due to your Lantus? I sure do.
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Permalink Reply by AfrezzaUser on
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No I actually have not had one severe low since on Afrezza. Lows were daily for me in the past. Needles dont scare me...I dont care about needles. Its the onset and lingering of Novolog and Humolog that scare me as I am super active person. As far as going back. I refuse to go back..The FDA has opened the way for people like me...Stay tune about that. To me its almos life or death as I have had too many close calls...I am probably one of every 20 diabetics that eventually will die of a low episode if I have to go back on Afrezza or Humolog. I really cant get a low from the Lantus dose I take..Afrezza does most of the work for me.
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Permalink Reply by drewgolden on -
Sign me up!
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