I have been on Afrezza now for months. It is an ultra rapid insulin that is inhaled. I been on it now for 4 months and it has changed my life as I have no more worries of nighttime lows or lows throughout the day. When I was on Humolog / Novolog / Humilin my lows were daily. As we know this is a killer among diabetics as 1 in 20 will die from a low blood sugar.
Last year I almost went into coma 2 times and barely got revived the 2nd time. I also have had numerous lows rushing to the fridge on Novolog and Humolog. This all changed 4 months ago. I have been needle free for 4 months other than taking my daily Lantus. I have had 0 severe lows and only a few lows under 70 in 4 months. I have no daily swings over 250 readings anymore.. Why is this? It is because my management with Afrezza is so easy when I can adjust my blood sugar in minutes. Afrezza is about 90% out of my system in 30-40 minutes after taking it. So lets say I eat a late meal at 10pm. I can take my insulin and at 11pm before going to bed if my sugar is good I know its impossible for me to have a low at night. This has freed from all the stress and scares of lows.
Not only has it effected me this way but all my family members have noticed that I never have any emergencies or rushes for sugar..They all are able to sleep well with no worried about me during the night.
So why am I saying all this?
It actually makes me ill knowing that most people do not even know that this is coming and should of been available to all diabetics already. People die every day of low blood sugar. How about kids that have to damage this disease and the parents who are worried sick every night. I am not even sure how they can sleep. The inhaler is the size of my pinky as the pictures shows. I can have it in my pocket wherever I go and take the insulin anytime anywhere. The insulin is in powder form in the little cartridges.
For me controlling diabetes is now in real time as I dont have to wait 1-2 hours for it to start working and lingering on for 4-5 hours. If my blood sugar is 300 and I can adjust to 100 in 25 minutes. It is truly amazing and if anyone is reading this and has experienced lows please free to ask questions.
I don't like this going 200 and dosing insulin and see if it comes down enough. It's all up and down BGs, you can have a great HA1c and still complications due to glucose variability.
And a time of action of 40 minutes is too short to cover carbs, and what about proteins that take 4 hours or more ...
And no precision at all, 10 or 20 units .... I dose half units ....
I'm not for it.
it has taken the swings our of the picture for me. I do not have lows or highs. On Humolog and Novolog I have always had big swings. I have not had these swings on Afrezza. As far as 10 or 20 units. You are comparing apples and oranges. 1 unit of Humolog does not equal 1 unit of Afrezza...I must say I have never in my life taken a half unit of insulin. Only 30% of type 1s use an insulin pump. If you never have lows and you are happy with it maybe its not for you. There are 30 million diabetics in the USA and 3 million of them type 1s. Out of that 1 million might use the pump so there are 29 million diabetics in the USA who could benefit. It does seem what Christy is saying is true that many here are over achievers etc etc etc.
You keep saying "it has taken the swings out of the picture for me" but then you say you take it before eating and if after 1 hour you are over 200 you take more, and many times you say you check and if it's high you lower it in minutes. It seems to me you are "following your BGs" instead of predicting them and avoiding highs.
Anyway I find interesting your experience, but I think this product would be very well suited for an artificial pancreas device.
An AP has a desperately need for a fast acting-short action insulin (and an accurate and robust CGM).
If only they could find a way to "spray" this insulin in the lungs through a device in a practical and confortable way ...
That was an example as a type one diabetic I doubt there is one person even on this board who never has a reading of a blood sugar of 200. I doubt there are any diabetics who can keep their blood sugar between 80 and 130 without ever going over that. So when I say it is high such as a reading of 150 I can correct it into the normal range in minutes. You make a great point about Predicting them. I been doing that for 10 years. You only need one prediction to be wrong and its all over. My only point is that this has changed my life and its working great for me. I am a person who does not want to wear devices attached to my body. I want to eat what I want to eat. I am very fit and active. I swim a mile at a time. I cant afford lingering insulin in my system. Not all products fit all patients. I am simply reaching out to people who have had low blood sugar problems and are looking for another solution. Most people do not follow a strict protocol as many here are following in their management of diabetes. The predicting of your blood sugar 4 hours from now after I eat and take Humolog and Novolog is not a simple process if you are a person who snacks often etc etc etc. I have many diabetic friends on the pump and they are having many problems with the lows. It is a big a problem as one in 20 diabetics will die from a low in their lifetime. I am sure I would of been part of that statistic. As mentioned many times I do not have that fear now as I really never worry about it. I am just a diabetic type 1 who has searched for a better mouse trap and I have founded it.
I can't guess the logic on how a spray insulin in fixed doses can avoid lows and highs.
I keep my opinion.
Yes, you are correct. See my reply to Garidan as perhaps 1 million diabetics might be using an insulin pump in the USA many others might be searching for another solution as they take diabetes control not seriously enough.
Afrezza user, Thank you for posting this information, but could you answer one question please? Do you own Mannkind's stock? Thank you.
That sure would explain a lot, wouldn't it Equestrian?
Maybe, but I'm not sure it would be worth the time. MNKD is trading about 2.5 m shares per day. I seriously doubt our little community could effect the share price in any way, if thats what we're getting at.
I think people are just curious as to why the OP is pushing this product as some kind of panacea and then ignoring questions about very real concerns when they are posed. (Such as how anybody could maintain stable blood sugar with only two dose possibilities, both of which are larger than most type 1's use.)