Afrezza An Ultra Rapid-Acting Insulin / Inhaled Insulin Onset 12 minutes!!!!
I have been on Afrezza now for months. It is an ultra rapid insulin that is inhaled. I been on it now for 4 months and it has changed my life as I have no more worries of nighttime lows or lows throughout the day. When I was on Humolog / Novolog / Humilin my lows were daily. As we know this is a killer among diabetics as 1 in 20 will die from a low blood sugar.
Last year I almost went into coma 2 times and barely got revived the 2nd time. I also have had numerous lows rushing to the fridge on Novolog and Humolog. This all changed 4 months ago. I have been needle free for 4 months other than taking my daily Lantus. I have had 0 severe lows and only a few lows under 70 in 4 months. I have no daily swings over 250 readings anymore.. Why is this? It is because my management with Afrezza is so easy when I can adjust my blood sugar in minutes. Afrezza is about 90% out of my system in 30-40 minutes after taking it. So lets say I eat a late meal at 10pm. I can take my insulin and at 11pm before going to bed if my sugar is good I know its impossible for me to have a low at night. This has freed from all the stress and scares of lows.
Not only has it effected me this way but all my family members have noticed that I never have any emergencies or rushes for sugar..They all are able to sleep well with no worried about me during the night.
So why am I saying all this?
It actually makes me ill knowing that most people do not even know that this is coming and should of been available to all diabetics already. People die every day of low blood sugar. How about kids that have to damage this disease and the parents who are worried sick every night. I am not even sure how they can sleep. The inhaler is the size of my pinky as the pictures shows. I can have it in my pocket wherever I go and take the insulin anytime anywhere. The insulin is in powder form in the little cartridges.
For me controlling diabetes is now in real time as I dont have to wait 1-2 hours for it to start working and lingering on for 4-5 hours. If my blood sugar is 300 and I can adjust to 100 in 25 minutes. It is truly amazing and if anyone is reading this and has experienced lows please free to ask questions.
Tags: afrezza, blood, control, dangers, hypoglycemia, inhaled, insulin, low, of, on, More…
Replies to This Discussion
-
Permalink Reply by Jethro on -
Normal pancreas sends insulin to the portal vein. I saw that on a website somewhere...I therefor assume that insulin is normally delivered intravaneously which is why it works so quick and is then done. The problem with subcutaneous injections is the delay and inconsistency in start / stop times.
My point is that inhalation could result in fast start times comparable to injecting directly into a vein.
-
Permalink Reply by Don on -
I'm glad you have posted your experience. I'm curious do you ever have to take several doses to cover slower-digesting meals? Surely your meals digest longer than 30-40 minutes when 90% of the Afrezza has already metabolized?
I love the ability to drop a high so quickly.
-
Permalink Reply by AfrezzaUser on -
Well 10% i would say sticks around for another 1 hour. Once in a while yes it does happen but it takes me only 25to 35 min min to correct it. You can do that with no crashes... Someone above posted about inhaling something into the lungs. I think its more normal to inhale insulin which is in the body anyways vs all the smog we inhale all day. There have been patients on this for 5 years with 0 safety issues. Until I went on the trial it is hard to believe what Afrezza does till I got to experience it myself. You could actually not even take Adfrezza at the meal but eat first knowing that you can adjust your insulin from any level in 30 minutes which would still be better than Novolog and Humolog from my experience. It seems many posters here have perfect control on the insulin pump. The people I know all have highs and lows and crashes but many here indicate they do not. 1 in 20 die of low blood sugar so its a big problem. That is way too high. Think about it if you eat and take your novolog your blood sugar spikes right away where as with Afrezza it really limits your spikes. It also takes a few week to get a hold of how works on your body and figure out the titration just like with any new treatment.
-
Permalink Reply by Terry on -
AfreezaUser -- Thank you for posting your experience with this ultrarapid inhaled insulin. It's short duration is an especially appealing feature. I will be watching for this to get through the FDA and come to market.
-
Permalink Reply by otter on -
This sounds pretty exciting to me... as does any true Ultra rapid insulin (injected, inhaled or otherwise). My onset time for Novolog/rapid is up to three hours, and remains in my system for up to 6 hours, and is very variable, a ultra rapid acting insulin would be a life changer for me. Thanks for sharing this information, it's something I look forward to following. Nice to hear that Afrezza has been such a good thing for you.
-
Permalink Reply by AfrezzaUser on
-
It has been a life changer for me. I wish it was not inhaled because all it does is distract attention from the true benefit. I really would not care if its injected/inhaled or whatever. I just needed something that worked real time like out damaged pancreas. I was on Novolog and the highs and lows and crashes are just too damaging. No more such problem.
-
Permalink Reply by Timothy on -
I did a study for exhubera study for 2 years. i had no trouble with the action of the insulin or the size of the inhaler( which was large, but more like the size of a meter)
the trouble with it was the size of the insulin caps. you had your choice between a 10 unit and a 3 unit cap. It was not possible for me to correct slightly high sugars. this caused my a1cs to go up. Secondly the power is an irritant and often i would cough in the middle of inhaling and have no idea how much insulin I took. And When I had a cold I had to go off the inhaled insulin all together.
the kicker though is that most of the people in the study had a decrease in lung volume and capacity. Mine has recovered though but it took years.The thing that i worry about most is that you are in violation of the study protocols by posting here. You are not permitted to talk to anyone, nor post on a website about any product that has not been approved. you are setting yourself up to be sued and you could invalidate the results of the study this way.
I know they warned you about this because the make you sign the standard form prohibiting it.
You have to know why, if other on the product read this, then they may falsely develop the same side effects that you have or lack of. Also you are undermining the companies right to keep the results private until they are ready to release them.
I would stop posting if i were you, but really to me it sounds like you are selling something.
-
Permalink Reply by Zoe on -
Thanks for the input, Timothy; that was the main question I had, how can you accurately manage blood sugar with only two choices in dose. The OP never responded to that question.
I think Spock had it right from the beginning; it does sound like SPAM which is against the TOS of this website. It's always a dead giveaway when you see a person who has only made one post.
-
Permalink Reply by AfrezzaUser on
-
Comparing Exubera to Afrezza is like comparing a Yugo to a Ferrari. THe only things the 2 have in common is that they have wheels. The only thing Exubera and Afrezza have in common is that they are both inhaled. There is nothing else in common with the 2 but if you are interested in learning more information it is out there. This is an open label study and I have read all 30 pages of what i signed 10 times over reading every word.
Thanks for your concern though. It is time to take a break that for sure.
-
Permalink Reply by rubidoux on -
I think there would be a place for this even in someone who was very well controlled on a pump. I don't normally need to bolus as much as five units for a meal, but I can't commit to never eating carbs again, so it may happen. And I think it would be great for corrections. I need five units to bring me down from 250, and that is not unheard of for me. And I do like the idea of something so quick acting if you need a big bolus close to bedtime. I sure hope they figure out how to make it in one unit increments. Smaller would be nice, but you could always do 2 units of Afrezza and .3 units through your pump.
It seems like a lot or all of the type I's in the trial must be using both Afrezza and normal insulin. It couldn't be that there are many people who can live with only five unit increments.
-
Permalink Reply by Timothy on
-
The study I was in for exhubera had me on Ultra lente as a basal( which I wason anyway) and exhubera only in 3 or 10 unit caps. I was not permitted to take anything else, So I let my sugars go higher. My a1c went from the high 6's to the mid 7's. After this study I went on my first pump and my a1c's came down to 6.7 or so and stayed that way until i started using cgm which brought me into the 5 range.
-
Permalink Reply by Zoe on
-
I mean that is what you would expect from such inaccurate dosing, so it's amazing to me it was ever approved. I know a friend of mine was on it very briefly (a type 2) but I never heard what was the reason they took it off the market?
I also question the statement that only 30% of us are on pumps; I don't have any official stats but it seems like a lot more than that!
Good for you for your success in lowering your A1C.
Advertisement
REsources
Groups
From the Diabetes Hands Foundation blog...
Congratulations Diabetes Advocates Scholarship Recipients!
The Diabetes Hands Foundation and Diabetes Advocates Program is proud to announce and congratulate the members of DA who were granted scholarships to attend diabetes conferences in 2013! Thanks to a generous grant from Novo Nordisk, in 2013 we were …Continue Reading
La Familia de EsTuDiabetes Sigue Creciendo
El Centro Nacional de Prevención de Enfermedades Crónicas y Promoción de la Salud en el Estados Unidos encontró que a partir de 2002-2009, el 11,8% de los hispanos mayores de 20 años, que viven en los EU, viven con diabetes …Continue Reading
TuDiabetes Team
DHF STAFF
 Manny Hernandez(Co-Founder, Editor, has LADA)
|
DHF VOLUNTEERS
Lead Administrator
 Bradford (has type 1) |
Administrators
 Lorraine (mother of type 1) |
 Marie B (has type 1) |
|
|
|
|
|
|
LIKE us on Facebook
Spread the word
This site complies with the HONcode standard for trustworthy health information: verify here.
© 2013 A community of people touched by diabetes, run by the Diabetes Hands Foundation.
