A little background info...
I was on Lantus and Humolog a few months ago, and that seemed to be working ok for me. 10-15 units before meals and I was ok. But my new endo switched me from humolog to apidra and I find that I take 30 units and my GLs are still sky high. I was charting it for a while and found that with a gl of 173 before breakfast, I took 30 units of apidra, ate a hard boiled egg and a bagel and my GL went UP to 385. WHAT?!? This just seems outrageous.
I get very frustrated and give up. Apidra just does not seem to be working for me. One night I got so angry I just decided to take as much apidra as it would take to lower my level into the normal range. So before dinner I took 30 units and ate a salad. Lettuce, tomatoes, green peppers, and ranch..THATS ALL I ATE. It took me 60 units to get my level into 118. This just dosn't seem right. And I'm frustrated.
Is any one else having problems with apidra? Is anyone having success with Apidra? *rips hair out*
I have an endo appointment on thursday btw.

Tags: apidra, glucose, insulin, level

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Did you get the vial of Apidra from your endo or from the pharmacy? I'd check the expiration date & even if it's not expired, I'd take it back to the drug store (if you got it there) & ask them for a new vial from a different lot number. There's got to be something wrong with the Apidra. It must not have be stored properly before you got it, expired, or just a bad bottle.

Man, is that frustrating! I'd be ripping my hair out & back on the Humolog pronto also. Did you doc mention why he changed it?

60 units to cover a salad is nuts! I'd be dead within 20 minutes if I took that much. Even if you're resistant to Apidra, that's a very high dose to have to so little of an effect.

Everyone's ratios are different, of course, but I've never had a problem with Apridra. One unit brings me down 55-60 points & my I:C ratio is 1:12 for Apidra, though I use Humulin R for meals because of other problems. I use Apidra to correct highs & it works quickly for me.
My insulin:carb is 1:6 or 1:7 on Apidra and my correction sensitivity is 1 unit per 26 mg/dL. I switched from Humalog to Apidra when Apidra came out about 4-5 years ago. But like Gerri, I can't IMAGINE taking 60 units at once. I'd be dead, too! I'm a pumper, so I don't take any long-acting insulin, but most days I take in 60 units for the whole day (basal+meals combined!). I have nothing bad to say about Apidra for myself. I have used it in three different brands of pumps, used it in injections, and it lowers my blood sugar exactly as expected and covers my meals without a long tail afterward.

Sounds like you need to talk to your doc about switching back. Or perhaps you've got a bad vial. Whatever the case, it is NOT working for you.
I use the solostar pen. And the way my insurance company works is that you have to buy the medications from them and not from the pharmacy. So I truely have no idea where they came from, and I have THREE whole boxes of the pens sitting in my fridge already paid for. I think 5 or 6 pens come in a box. I'll deffinately check the exp date though.
Maybe you should use another new pen & see what happens. Don't take a large dose. There's got to something wrong with the pen you used. Wouldn't be the first time insulin had gone bad.
If that's the reason I'm going to cry. LOL. WEEKS of frustration over it. HAHA I'll keep yall updated though.
Very aggravating! Check the lot numbers on all the boxes also. If they're all the same, have the insurance company replace them all. Raise hell with them, if you have to. You can't take a chance using ineffective insulin & end up DKA.

Hoping it's just that one pen, or that one box, but they still need to replace what's gone bad.

I had a bad vial of insulin. It looked fine, wasn't cloudy, but it didn't work. Took it back to CVS & they checked all the lot numbers to find me a bottle that was different. They got me one from another store & told me they were sending them all back.
so I know this may sound retarded...but how do you know if you have DKA?
You'll feel really sick. Nausea, vomiting, exhausted, unquenchable thirst & constant peeing. Like the flu, but worse. You'll be severely dehydrated. Of course, your BG readings will be very high & you'll have high ketones in your urine. Not trying to scare you, but DKA is nothing to mess around with & needs hospitalization. Your insurance company gives you any grief about replacing the Apidra you tell them that you could die from their bad insulin.
Understand how you feel. I'd be screaming like a mad woman. Let me know what happens.
Apidra did not work for me. I did not finish the whole trial bottle..my endo says like anything else...it just doesn't work for seom peeps.
Same with me ..... grrrrrrr... two endos prescribed solostar and apidra ... 45 units for the whole day for solostar and 25 units of apidra before meal and my sugra is alway 220 ..... but one time i had a hypo for a day same diet .... I used to take humulin 70/ 30 and it was a lot better .... problem is i have 2 months supply of this solostar and apidra .....
By the way .. its one month now since i have been using solostar and apidra ...... my doc had me started at 40 units solostar and 10 units apidra per meal .... no improvement at all.

I inquired about Humalog Mix 25 .....

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