Replies to This Discussion

Permalink Reply by acidrock23 on April 19, 2011 at 4:23am

I agree that's great news!! I hope that it becomes readily available for everyone SOON and at a reasonable cost, without any interference from insurers or the FDA!!

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Permalink Reply by BadMoonT2 on April 19, 2011 at 5:41am

Here's a well written article, from BusinessWeek of all places, that goes into more detail about the study and its implications. Unusual for things written in the popular media, it explains the difference between T1 and T2.

Unfortunately the drug tested, which decreased insulin resistance, apparently also has significant side effects so don't hold your breath concerning a miracle cure on the horizon. But this study would seem to signal a paradigm shift.

The final paragraph is:
"People with type 2 diabetes are often blamed for bringing the disease on, but it's a combination of genetic and physiological factors exposed to a certain environment. And, this study points out what may be another important biologic factor,"

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Permalink Reply by Holger Schmeken on April 19, 2011 at 6:35am

Thanks for this link. So according to the article obesity can trigger stress and inflamation > inflamation can lead to the production of antibodies against fat cells > attacked fat cells are insulin resistant and are hindered to process fatty acids. The drug anti-CD20 dampens the immune system and then the attack stops (in mice).

It would be interesting to know if non-obese T2 patients also have these distinct antibodies found in the study.

The bottom line: T1 and T2 have more in common than I thought.

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Permalink Reply by KimKat on April 19, 2011 at 6:38pm

Yes, what about us Thin Type 2's?

There are lot more things that can trigger stress and inflammation than obesity that is for sure. Some people think that certains foods cause in inflammation like an allergy to gluten.

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Permalink Reply by Michele on October 1, 2011 at 3:42am

Anti-CD 20 monoclonal antibody, Rituxan, is the $6200 drug I am getting for my life threatening lupus, which United Health care has refused to pay for. Drug has excellent promise for all autoimmune diseases. I asked if it would help my thyroid or pancreas. doctors laughed and said those are already DEAD!

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Permalink Reply by Lightsinger on October 4, 2011 at 7:00am

Here's a well written article, from BusinessWeek of all places, that goes into more detail about the study and its implications. Unusual for things written in the popular media, it explains the difference between T1 and T2. Unfortunately the drug tested, which decreased insulin resistance, apparently also has significant side effects so don't hold your breath concerning a miracle cure on the horizon. But this study would seem to signal a paradigm shift.

The final paragraph is:
"People with type 2 diabetes are often blamed for bringing the disease on, but it's a combination of genetic and physiological factors exposed to a certain environment. And, this study points out what may be another important biologic factor,"

It may not be the cure, but it certainly seems to be going in the right direction. At the very least, the study points out what many of us have known for a very long time: this isn't something we did to ourselves! If being overweight was the cause, then every overweight person in the world would be diabetic, and that's just not the case.

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Permalink Reply by Christalyn on April 19, 2011 at 6:15am

Wow!!!

Still the best "cure" for Type 2 diabetes is prevention and education especially in the African American and Latino areas. These groups have the most to benefit from this but never get the information. but still this is good news. I doubt a "cure" for Type 2 diabetes will be around the corner.

Thanks for the article!

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Permalink Reply by gphx on April 20, 2011 at 5:01am

There is no prevention of T2 diabetes. There is no cure either. Claims to the contrary are b*******.

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Permalink Reply by Donna H on April 19, 2011 at 4:34pm

WOW! Thanks for posting this.

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Permalink Reply by Linda G on April 21, 2011 at 2:25pm

Personally, for me it's not the overweight issue
directly, but more that most uneducated people ASSUME that type 2 are
overweight...supported by the media, as well as some medical personel....
how are we to target the "culprit", if the assumption is that it is predominantly
a weight related issue. It hurts me personally and countless others,
as we have NO excess weight to lose, and STILL battle highs and lows!!
It's enlightening to read that there was actually a study conducted in support
of what I had always suspected....an autoimmune reaction!!!

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Permalink Reply by Lila on April 21, 2011 at 3:26pm

Tragically, it is not just uneducated people. I'd say probably the majority of ALL people, even educated people, assume that Type 2s brought it on themselves due to 'bad' lifestyle.

And even if you succeed in getting through to ONE person, you are just the maverick voice espousing the non-standard view. Five minutes later, that person you managed to persuade is going to be bombarded with the mainstream view that Type 2s did it to themselves (heck, that all diabetics did it to themselves).

I hear the mainstream view so much that sometimes, even I have to stop and think, and ask, surely I must have done something to bring it on?

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Permalink Reply by KimKat on April 21, 2011 at 4:02pm

Geez, if that was really true - I mean, look at all the unhealthy people walking around! 99% of the people on the planet would have Type 2 is this was really true. Unhealthy diet, obesity, smoking, alchoholism, no exercise, etc.

Let them stereotypers show me the proof WHY I got it and all the other unhealthy blobs walking around don't have it! Than we'll talk... :)

I'll a total toothpick, as some of you know, and I always have been. I am gonna get me a tee that says I have Type 2 and let people look at me in disbelief. I should even go on the news.

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