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I wonder if people diagnosed as Type 1 at older ages (let's say 18+) have different genes involved than those who are diagnosed at younger ages (under 18). I see a lot of people with multiple Type 1s in the same family where everyone was diagnosed as a kid or teenager, and others where everyone was diagnosed as an adult. Maybe that might explain the differences in insulin production, etc. as well.
I was diagnosed at age 9 and have absolutely no diabetes (Type 1 or Type 2) anywhere in my immediate or extended family.

Permalink Reply by Judith on November 7, 2011 at 8:52pm 
Permalink Reply by Gerri on November 7, 2011 at 11:21pm
Permalink Reply by BadMoonT2 on November 8, 2011 at 6:10am
Permalink Reply by suezq1949 on November 8, 2011 at 12:54pm 
Permalink Reply by Judith on November 8, 2011 at 4:13pm Ouch indeed, Muragaki. I also have questions about the complexities---so I had a genetic risk, but I have come to believe there are "tipping points" involving trauma and/or inflammation and/or maybe the alignments of the planets!......
Judith, do you remember the kinectic toy that was five steel balls suspended from a wooden frame? If you pulled back one, two or three then let them go, they would strike the remaining suspended balls and create an opposite reaction of either one, two or three at the other end.
That's how MY planets have aligned...
Permalink Reply by wickhamster on November 8, 2011 at 5:29pm So does this come down to 'what caused it?
Meeting with a new doctor here, told him I have type 2 (diagnosed years ago) and added that I have haemachromatosis (iron overload) and this possibly caused it ...
To my surprise he said, 'now that changes everything. that completely changes my attitude to you.' So if it was my fault (caused by obesity perhaps) ... what was he going to do? But as this wasn't really my fault, maybe even caused my obesity ... well that's different, he was willing to be nice to me.
Heamachromatosis, in theory, affects 1 in 300 of 'northern European' genetic extraction. As a fair-skinned caucasian, that puts me in the box.
When I was in the UK I went to a clinic to check my ferretin levels, and they were so excited to see me, and couldn't believe that (in Australia) I had already been tested and was aware of my condition. They said they are expecting to find a lot of people with the condition, but unaware of it, and displaying in in ways such as diabetes which it can cause. They go to diabetes clinics to find people with it - but it hasn't been turning out as they expected.
Anyway, the point is, people over 50 with haemachromatosis tend to have quite a build up of iron (especially women past menopause), and this can initiate diabetes ... apparently.

Permalink Reply by Judith on November 8, 2011 at 6:12pm "down to what caused it"?.....Well I have come to believe it is much too complex for such simplistic questions.Diabetes is likely to cause obesity, for instance--chicken and egg.
Rather it is an interesting discussion of possible contributing factors, about which I am convinced we all here provide a much more complete picture than overly simple studies and one-size-fits-all dx.....
Manny Hernandez(Co-Founder, Editor, has LADA)
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Bradford (has type 1) |
Lorraine (mother of type 1) |
Marie B (has type 1) |
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