I have noticed that when I eat right before bed (and bolus correctly), I almost always wake up with high BG. I suspect that the role of active insulin changes during sleep, from glucose metabolism to one of the functions listed below (via www.diabetesinformationhub.com).

"Functions of Insulin

In addition to its role of regulating glucose metabolism, insulin also

Stimulates lipogenesis
Diminishes lipolysis
Increases amino acid transport into cells
Modulates transcription
Altering the cell content of numerous mRNAs
Stimulates growth
DNA synthesis
Cell replication"

I recall from biology courses that a few of these functions happen primarily during sleep, so I think that as a rule of thumb, it is best to hit the pillow once the bulk of any active insulin has finished its work.

All opinions, thoughts, etc. will be greatly appreciated,

Brandon (T1 dx 07/21/12 - Minimed 523 no CGM)

Tags: active, bg, bolus, function, glucose, high, insulin, metabolism, sleep

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i notice the same thing. honestly best not to eat before bed for me.

If I snack on just some celery w/ranch dressing I'm fine in the morning but if I have a couple of pretzels (which I love) I'll be high in the morning even if I bolus for them.

Some of you seem okay with higher blood sugars at night; personaly I don't sleep deep if I'm above 130. That lack of good sleep translates into poor absorption the following day.
I use the T slim pump and have it set to deliver slightly lower basal between midnight and seven am. I try to avoid eating after 9pm. I wish I could say I have this all figured out but I don't. High bs equals poor nights sleep and low bs could equal seizure NOT GOOD...
Peanuts are good to help avoid A.M.lows because they break down slowly but if A.M. highs are the problem stay away from peanuts.
I hate this freakin disease and wish we could all get together and find a way to promote public awareness and the need to support research for a cure.

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