What time do you take your bedtime injection? I usually take mine around 9PM but wondering if there may be a better time to take it? I never understood how Lantus could be effective at night time being it releases at an even keel so how does it cover the liver dump around 3pm or so? For that reason and the cost I've stuck with NPH and most of the time I seem to do OK with it. I have a feeling after these severe low Incidents they are gonna suggest Lantus. I guess if it prevented the night time lows I'd opt to use it despite its enormous cost.

Views: 324

Reply to This

Replies to This Discussion

I think if you go low a lot your liver never really has a chance to store up enough glucose to release it at times when you're low, so going low a lot could cause your liver to not be releasing enough glucose as it should.

For me my blood sugar swings on NPH were just way more dramatic than on Lantus and/or the pump. No matter what I did I was either going high or going low.

Jen,

I only use NPH at night. During the day I use both R and Humalog depending how they are running. In essence I have no background insulin during the day but R stays hanging around for 5 hours or so. Its really a shame that Smart Insulin more or less is sitting in limbo. If it had worked as suggested it would have been life changing for all of us. I still refuse to give up on a breakthrough treatment down the road. I think it will eventually happen, just a lot further away then I anticipated. I think both of us like many have more then paid our dues and we deserve a betting ending. As a youngster I never invisioned diabetes taking the toll it has on my life thats for sure

@Gary: I think it is a big mistake to use the NPH only at night. The basal should cover your basic needs. This way you can skip a meal or get sick without being forced to eat something. The bolus insulin should just be used to cover the carbs to eat and for corrections. If you cover your basal needs with a part of the bolus it is not the right approach. Basically your regime causes that you have less insulin than you need for at least 12 hours. In other words you are running dry on insulin and all the little bolus shots you are using over the day are an incomplete replacement for the missing basal insulin. This can cause the fluctuation in blood glucose that you do not like. It is a bold step but why not splitting the dosage in two shots 12 hours apart? With some testing of the basal rate you will find out how much more you need to inrease the dosages of the two shots to get even levels. Ok, even in the sense of what is possible with NPH. With two shots of basal you will have to find new I:C ratios that is for sure. Yes, it can fail and it can even cause lows. But I really think it is worth to try something different here.

I use NPH because of cost (out of pocket) and availability. NPH is also preferred by my endo considering I am pregnant. However, I have been using NPH ever since (and Humalog to cover meals).

I use NPH twice in 24 hours. It's profile seems to work fine for me, and particularly blocks the dawn effect. I take a morning dose at about 7 am and an evening dose at about 10 pm last thing before sleeping. I usually don't eat after about 7 pm and eat very lightly in the evenings so I don't have significant bolus insulin on board by the time I sleep.

I like to go to bed with BS in the range of 80 - 100.

Obviously this gives me some overlap in the mornings if you assume a roughly 12-hour profile.... but I am much more insulin resistant in the mornings and so this works for me. I dont' get overnight lows.

I do get a bit low late morning sometimes. This means I need to either have lunch on time by about 12:30 pm or suck a piece of hard candy to tide me over until I get to lunch.

But this could also be becuase I need quite a lot of Humalog for breakfast and this is the end of it's effect.

The trick is to get the basal rate right, so that your levels are pretty stable even if you don't eat. This can be achieved with a bit of experimentation.

I also had pretty good results w/ NPH consistently whenever I'd drink a ton of hard liquor. Beer wouldn't do it, just the hard stuff. It probably took a dozen years off my life. Oh well...

I use NPH for my basal. I take my night-time dose before sleeping. Usually around 11. It seems to work perfectly for me as far as it's peak action and stopping the dawn phenomenon and I don't get overnight lows. But I need my next dose of basal around 8 am latest, else I'll start rising above target.

Seeing it works so well for me, I've no intention to change.

Do you take NPH just once per day?

Answered above. Twice a day. Currently 28 units at 10 pm. And 30 units at about 7 am. Before pregnancy dose was a lot lower.

@Super_sally: Gary wrote "I only use NPH at night." so I think you have got that wrong.

RSS

Advertisement



REsources

From the Diabetes Hands Foundation blog...

FDA Docket Extended! We Need You.

If you are new to diabetes advocacy in the traditional sense of the word, you may be thinking, “What the heck is a docket!?” I certainly was the first twenty times I heard it (yes it took that long). For Read on! →

An Open Letter from @AskManny, @DiabetesHF to @NYTRosenthal, @NYTimes

Dear Ms. Rosenthal: I am a person living with type 1 diabetes since the age of 30. I am also the President and co-Founder of the Diabetes Hands Foundation, a nonprofit aimed at connecting and mobilizing the diabetes community. Seeing Read on! →

Diabetes Hands Foundation Team

DHF TEAM

Manny Hernandez
(Co-Founder, Editor, has LADA)

Emily Coles
(Head of Communities, has type 1)

Mila Ferrer
(EsTuDiabetes Community Manager, mother of a child with type 1)

Mike Lawson
(Head of Experience, has type 1)

Corinna Cornejo
(Development Manager, has type 2)

Heather Gabel
(Administrative and Programs Assistant, has type 1)

DHF VOLUNTEERS


Lead Administrator
Bradford (has type 1)

Administrators
Lorraine (mother of type 1)
Marie B (has type 1)

Brian (bsc) (has type 2)

Gary (has type 2)

David (dns) (type 2)

 

LIKE us on Facebook

Spread the word

Loading…

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information: verify here.

© 2014   A community of people touched by diabetes, run by the Diabetes Hands Foundation.

Badges  |  Contact Us  |  Terms of Service