Replies to This Discussion

Permalink Reply by Vancouversailor on November 7, 2012 at 11:58am

When choosing between different research areas and projects, a msjor consideration for scientists would be the likelihood of success. I think most people would agree that the chance of finding an actual cure for type II is about the same as finding a way to prevent someone who jumps off a ferry on a dark and stormy winter night, from drowning.
A cure for type I is a lot more tangible, as we are dealing with chemistry and physical functions of the human body rather than personal, ingrained lifestyle choices. So not surprising that type I research gets priority.
The solution? Forget the talk about a 'cure' for type II diabetes. Instead, focus on adding new and effective tools to two areas that are achievable: prevention and management.
Neither fits the definition of a cure, but they arguably are a good second best.

Permalink Reply by Stemwinder on November 7, 2012 at 2:26pm

I'm not so sure that T2 is not curable. There are a lot of people that lead the classic T2 lifestyle and don't get it. Something pushes us T2's over the edge and I think that is curable. Lifestyle isn't the only cause.

Now curing lifestyle issues is something more difficult.

Gary
.

Permalink Reply by jims on November 7, 2012 at 4:44pm

I do not quite agree here. The problem in my mind is the fanaticisim to seek out single in middle of target center solutions that are a magical solution that one fits all.

After 30 years my experience as type 2 and nearly rotting out suggests the following:

a) metformin to stop excess liver glucose release.
b) while some folks call it lifestyle fixes which is not necessarily wrong but a bit broad sepctrum based and from my view really is energy balance. One needs ro ensure energy supplied from liquid energy more closely matches present energy burn so weight not increasing. CHronic over energy supply - liquid glucose ends up loading up the skeletal muscles temporary storage as well as for many adding many extra pounds. Once muscles saturated, insulin resistance goes up and glucose backs up in blood system. Plus sufficient strong exercise.

c) adding insulin boost on meal bolus for aging pancreas and ensuring basil insulin releases are adequate. ( Lantos use etc)

The above in order of steps taken to arrest nasty type 2 liver driven diabetes.

My read is that there are answers to type 2 but require a quiltwork of fixes as well as energy balance (lifestyle) and exercise to realize.

The human chemical plant is really quite complex and present tools focus almost soley on insulin and pancreas and ignore the balance.

There are a host of hormones and interaction from liver, stomach, intestine, thyroid, kidneys and pancreas that really need to be observed real time and the system tuned back into the proper operating quadrent to arrest type 2.

Permalink Reply by Stemwinder on November 7, 2012 at 4:55pm

I suppose your right Jims. There are so many factors but I can't help but believe there is some commonality in most T2's. But who knows it may be just wishful thinking on my part.

Gary

Permalink Reply by jims on November 7, 2012 at 5:20pm

Stemwinder:

I am not right nor does right have point here and apologize.

Probably when one looks thru most cases ( and I have not), there will be commonality of probable causes covering most folks. Thats just good science attempting to quantify the cases and issues to identify cures/treatments for those constrining costs.

For me as my Doctor indicated, I am out there not typical of the standard cures and approaches but in end managed to get mess hauled in once the excess glucose and issues coralled and from there much more standard.

All I can relate to is the computer/digital/microprocessor electronics I have worked on and solving critical messes and disasters and one item stands out that as complexity and speeds increase, complesx high speed debugging tools to watch 200 to 400 signals at nanosecond speeds at real time to idenify who burped and sent the whole process awol.

Current technology neing used on T2 diabetes is in my mind most disappointing and inadequate. We have got to cgms - great but no cigar!

It is no surpise to me T2 numbers are exploding out of control and we are making poor progress. This is no insult to all those Doctors and folks working this issue that from my perspective from what I have seen is a miracle they are doing the job helping folks as well as they do. No complaint or insult intended.

Permalink Reply by Pauly on November 7, 2012 at 5:13pm

Meeting with a dietician would be in order to get some helpful ideas and a good plan for your meals so you eat properly at this stage.

If your not getting answers or results from this endo go to another one. Your BG is too high and this is something you cant wait on and it needs attention. Good Luck

Permalink Reply by jims on November 7, 2012 at 5:41pm

Good point. Thank you.

Permalink Reply by jims on November 19, 2012 at 9:19am

I cannot find response by Mark?

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