Gary, I wish phoning would help, but by the time a new study gets written up for the Institutional Review Board, etc. etc., this is a long way off.
The population was very, very tiny.
There's a long way to go.
Probability statistics have to be dealt with.
Choosing a population for this will be by dice. Of course there's other ways, roulette wheel? random draw?
The way I see is be a guinea pig or die. I can't handle the sugar swings anymore. I honestly for the life of me can't understand how anyone can tolerate living with this. It's like a plaguing cancer. Sugar swings are like chemotherapy. Besides the complete misery of feeling like hell I've come close to death a few times from night hypos that I couldn't on my own save myself. It would be not easy to purposely overdose on insulin but without a cure it would honestly be the best case scenario for both me and my aging folks. No one can tell me any different that living like this is living hell. Quite frankly I could care less what the FDA thinks. Their lives aren't being threatened, my life is. I should be allowed to opt for any treatment I want. I'm so sick and tired of waiting around for a breakthrough while I'm suffering away.
Gary I agree if someone chooses to be a guinea pig, given that they have all the available information about the research then it should be allowed, no one loses because the research is happening anyway in fact the research teams will benefit from it.
Of course while you're waiting for a cure (and I wouldn't recommend holding your breath) you could try working on reducing your A1C, not to mention getting support for mental/emotional issues.
Just saying. It gets hard to know what to say to someone who keeps posting desperate pleas and then finding something wrong with every suggestion he gets.
Maybe I should just say something obscure like AR:
L-D-N!!!! LOL - AR you're getting more mysterious than ever!
My A1C's are fine and my sugar control is not too bad in general but I just believe without my own pancreas working I will never feel well. I had two glucose readings this week of 121 and 113 2hrs post injection and was physically and mentally disturbed from them. Slight cotton mouth, pressure in my hands, irritability.I was actually expecting much higher levels based on the way I felt but it doesn't take much. I believe that diabetes screwed up my whole central nervous system. There is no reason I should feel anything but perfect at those levels but I don't. My only option is constant low sugar which isn't good either and more dangerous but I don't have much choice.
#1-Your profile says your A1C is 8.5. that's not fine. Last time someone called you on that, you said it was in the 5's, but never changed what your profile said.If I'd gone from 8.5 to the 5's I'd be bragging about it!
#2-You have been told a couple thousand times that you quite obviously have emotional issues aside from your blood sugars, and it would make coping with diabetes much easier if you confronted those issues. You have decided a thousand people are wrong and that you are specially sensitive and uniquely tragic. It get's manipulative and it gets old.
Gary have you had chemo? I think you said you hadn't. How dare you compare anything to chemotherapy, which I have had.
The problem is unless a trial was done locally I don't think I could realistically pull it off. Based on the info the procedure appears extremely safe at least in the short term. I would so love to be involved in any cure related research. I think it would actually give me a feeling of hope that I just don't have sitting in front of a computer typing. I'm truly amazed that this trial was done on humans already and is clearly showing signs of disease reversal. Even more so then Dr Faustmans work or any other trial for that matter. The trial was done in China probably because the FDA here drags crap out till no end. I will follow this one closely and pray it doesn't just disappear. They are apparently moving forward to a larger group of people and shooting to see if they can get people off insulin altogether. That in my mind is the only way I'd consider anything an effective treatment. Having to use less insulin and having overall tighter control would be beneficial but its far from freedom.
I've always assumed stopping the Tcell attack would require us to understand why the Tcells start firing on friendlies. With this study, they don't even have to understand how the stem cells are re-educating the Tcells. A short 3 hour remedial class is all the Tcells need. And it sounds like it could be cost-effective (and maybe only 1 treatment needed). I would love even a small regeneration of beta cells. My bg control was much, much easier when I still had a little bit of beta cell function left.
Maybe it would be best for this to develop outside the US so it can move along faster. Once proven with lots of supporting data, it can come to the US and hack it out with the FDA.
I to think this one sounds promising Don, the problem with the current direction of most research seems to be that the majority of the researchers do not yet seem to accept that insulin producing islets do seem able to regenerate as now proven by Dr Faustman and now Dr Yong Zhao they seem so set in the belief that once the cells are dead then that's the end...I think research will follow this new direction and someone will be working on a t cell educator vaccine but sometimes the powers that we have to restrict bad drugs coming onto the market stop good stuff moving forward and unfortunately this seems to be more so on your side of the pond where most of the big research could come from :-(
I found this an interesting read and the links at the bottom of the page shows some other work starting in Qatar and Australia