I've done some research on the epidemiology of Type 1 in the US. I can't seem to find a reliable number that reflects either the entire population of Type 1s (children and adults) or, especially , those who live with Type 1 who are under the age of 19. The CDC page (link below) says that 13,000 young people are diagnosed every year in the US. Simple math (too simple, I know, but follow the thinking) says that 13,000 x 19 = 247,000. On the same page it says that the incidence for young people is 1.7 per thousand. The US Census says that 28% of the US population is under the age of 18 - 85 million. 85,000,000 x .0017 = 144,500. (close to the 151,000 noted on the same page).
The JDRF page says that 15,000 young people and 15,000 adults are diagnosed with Type 1 each year = 30,000 total. The average lifespan of someone who lives with Type 1 is 68 years (simple math - I know too simple...but) says that there should be approximately 2 million people living with Type 1 in the US. That number seems high but the JDRF says it is as high as 3 million.
Interested in anyone's take or help - I'm not a mathematician or statistitian.
Sorry i mean T2 in 2015 there will be more with T2 2015 i said 2012
To my knowledge it is Finland that has the highest incidence rate of T1 diabetics in the world 40.9 per 100000/year (see here). But perhaps the study is outdated now.
Holger am getting new DATA in the morning about europe but i no that sweden and norway and demark and the UK are very high may be the DATA i got is that may have highest per pop in europe for T1 as in total numbers and not per PP of 100k i will find out
that is very very old DATA lol
Holger, do you have any idea why the autoimmune system would target beta cells but not alpha cells? Just curious.
Interesting question. Do people exist that have lost the capability to synthesize the peptide hormone glucagon due to alpha cell loss? This condition would not be life threatening but life altering. Perhaps these are the people that tend to lows although they are otherwise healthy?
In general the autoimmune system of T1 is attacking all sorts of tissue. I mean we are all prone to experience multiple immune conditions in our life: thyroid, beta-cells, rare skin conditions etc. Why not alpha cell loss? It is just a question of probability.
Well, there are people in the general population who are chronically hypoglycemic. Possible that could be a cause, or one of the causes. Probably some research out there if one went looking.
beta cells outnumber alpha cells in human islets.
It sometimes isn't just the beta cells that are attacked. That is why people with T1 can benefit from things like Symlin, which is a synthetic form of Amylin, made by another cell type in the pancreas (delta cells??).
Plus, people with T1 are more likely to develop other types of autoimmune diseases, in particular Hashimoto's hypothyroidism and celiac's disease.
Actually, Amylin is produced by the Beta cells.
You are right! Thanks, Sam Iam!
My brother and I are both Diabetics I'm a T1 and my brother is a T2 we are both insulin dependent skinny and our parents are in their 80's and in very good helth...we are not sure either one of us will survive them. Our children's ages are between 31 and 45, none of them have diabetes. We both see the same Endocrinologist and he says we fit into a group that makes up maybe 2% of the diabetics he sees at the clinic.