I requested the article from O. Rolandsson and Jerry Palmer, "Latent Autoimmune Diabetes in Adults (LADA) is Dead:  Long Live Autoimmune Diabetes!" from Dr. Rolandsson, and he kindly sent me the PDF.  Very interesting!  I have attached the article.

Tags: 1.5, LADA, Type, autoimmune, diabetes

Views: 63


Reply to This

Replies to This Discussion

What did you take from the article, Melitta? I got bored pretty quickly. Are we now AD's as opposed to LADA's?
The bottom line is that autoimmunity is present in diabetes.
The presence of autoimmunity is in non-diabetics as well as in diabetics.
Classification of subsets is useful in research pathway determination: for science.
Subset classification may not be as useful in therapy determination.
Elaine: I got multiple things from this article, most of which I knew already but it was good to see summarized in one place, and also I am glad to see that superb researchers "get" some of the things we face (we who were diagnosed with Type 1 as adults). First, they clearly state that new-onset autoimmune diabetes is more common in adults than children. Then, they make the case for eliminating the term LADA, which I think is a good idea. Even though the term LADA was useful to draw attention to this large population of people with autoimmune diabetes who were almost always misdiagnosed as having Type 2 diabetes (a different disease altogether), the term LADA also allowed diabetes organizations, researchers, and MDs to marginalize adult-onset autoimmune diabetes as "rare" ("rare" but way more common than childhood-onset autoimmune diabetes) and not give it the attention I believe it deserves. For example, there is substantial evidence that putting ALL people with new onset autoimmune diabetes on intensive insulin therapy as soon as feasible greatly reduces the risk of complications. But many doctors insist on initially treating LADAs with Type 2 treatments, which hastens the destruction of remaining beta cells and leads to poorer outcomes for the person with diabetes.
I recall reading that the thinking had changed on initially prescribing T2 treatment as a "cover all bases" adjuct for newly diagnosed adult patients, for the reason you state, shortly after I was treated that way at diagnoses 6 years ago. I have been surprised at the number of new Tu members still witnesssing that protocol.
Thanks for posting the article, Melitta.




From the Diabetes Hands Foundation blog...

DHF receives $200,000 grant from Novo Nordisk

Grant given to support programs aimed at bringing together people touched by diabetes for positive change BERKELEY, CA: December 4, 2014 – Diabetes Hands Foundation (DHF) has received a grant of US$200,000 from Novo Nordisk to support programs aimed at Read on! →

Guest Post: World Diabetes Day 2014 on Twitter… sifting through the data

At Symplur we track hashtags, keywords, user accounts, and pretty much anything else on Twitter that has to do with healthcare. We collect the data and then build countless ways to slice it up so that we’re able to better Read on! →

Diabetes Hands Foundation Team


Manny Hernandez
(Co-Founder, Editor, has LADA)

Emily Coles
(Head of Communities, has type 1)

Mila Ferrer
(EsTuDiabetes Community Manager, mother of a child with type 1)

Mike Lawson
(Head of Experience, has type 1)

Corinna Cornejo
(Development Manager, has type 2)

Desiree Johnson  (Administrative and Programs Assistant, has type 1)


Lead Administrator

Brian (bsc) (has type 2)


Lorraine (mother of type 1)
Marie B (has type 1)

DanP (has Type 1)

Gary (has type 2)

David (has type 2)


LIKE us on Facebook

Spread the word


This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information: verify here.

© 2014   A community of people touched by diabetes, run by the Diabetes Hands Foundation.

Badges  |  Contact Us  |  Terms of Service