I intend to blog about this, but just want to share that, for me, Symlin has been the answer to the weight gain and increased insulin resistance since starting insulin injections last January. Until then, I was within normal weight range but after insulin, the weight started slowly creeping up. With every pound, I required more insulin.........and after 10 months, I was 20 lbs heavier - despite very low carb and exercise (my last A1c was 5.4).
Briefly - Symlin is a synthetic form of amylin (a hormone that is naturally created & released along with insulin, but also stops being released once beta cells are shot).
For me, replacing this missing hormone was the answer I've been searching for to stop the horrible cycle that Bernstein talks about in his book...insulin is introduced in someone who is already insulin resistant and it increases weight, every pound of weight increases resistance, higher resistance increases need for more insulin, more insulin increases weight, and on, and on, and on.
Nothing else worked before Symlin. It's been a little under 3 weeks, I've reduced my insulin usage to less than half what it was, and I've lost 8 pounds. Thankfully, I have not experienced any of the nausea that some people experience in the beginning.
By the way, another benefit of Symlin is that it also suppresses appetite. I am actually amazed that it is not used by more diabetics. It can be used by either T1s or T2s who are insulin-dependent.
I just wanted to share and spread the word............I know this is an issue for many diabetics and I am amazed that using Symlin is not more prevalent. I can deal with diabetes - but NOT with weight gain.