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Permalink Reply by 2o1ckvyr2zhft on January 28, 2012 at 12:17pm

the auto-immune system looks at everything in the body and determines is this SELF or NOT SELF.. in a diabetic the A-I system has determined that the islet cells that produce insulin are NOT SELF and need to be killed, so the body launches an attach on the pancreas.. i think they need to develop an immune suppressant that targets this specific A-I reaction... it sounds simple, but in reality, who knows...

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Permalink Reply by Natalie ._c- on January 28, 2012 at 12:26pm

Yes, you've quoted an over-simplified verbal explanation suitable for the masses who are not scientists. That does not begin to explain what molecular or enzymatic interactions cause the immune system to fail to identify islet cells as self, how genes interact with, and what molecules actually trigger the attack, why it centers on the islet cells while other autoimmune diseases target other organs, what makes some people susceptible to this attack and others not, and lots more questions I'm not knowledgeable enough even to ask. That's what I mean by WAY complex, and not enough known!

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Permalink Reply by 2o1ckvyr2zhft on January 28, 2012 at 1:39pm

natalie.. i hope you have a chance to see that youtube interview i mentioned.. he mentions good endorphins and their positive effects on the body...i'm just headed out the door.. i hope i get a chance to learn from you again... rob

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Permalink Reply by MeganB on January 28, 2012 at 12:40pm

Wel,I have to say YES. Because, I just attended a Diabetes Conference last week for health care professionals and the speaker had said they have cured type 1 in mice (yes, I know we are not mice) and that she strongly believes with the research she has done and seen, that it will happen soon. I know it is just one person's opinion, but it made me believe.

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Permalink Reply by 2o1ckvyr2zhft on January 29, 2012 at 11:55am

do you remember the name of the speaker at the D conference that said they have found a cure for diabetes in mice.. is their a web address i could visit to find out more...? thanks for your help meganb

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Permalink Reply by Regina on January 29, 2012 at 6:43am

No.

We're a BIG and lucrative market.

I work in an industry that has innovated and destroyed industries, but auto-immune diseases are interrelated. I've come down with hypothyroidism and that's probably 100% due to having a system that's goes on the attack every few years or so. Plus, I just don't think the science is where it needs to be.

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Permalink Reply by acidrock23 on January 29, 2012 at 8:45am

I think though that all of the current "cure" prospects are aimed at fixing people after they break, which will still leave a market in place for newly dx'ed people who'd develop diabetes? If the product is priced correctly, likely fairly expensive, no insurance company in the world would be able to argue against it as it would still be cheaper than $15 worth of test strips every day and forever, not to mention the other stuff?

I think that the cure should be considered a public health crisis since the public, overall, has to fund "coverage" whether it's through an entirely public health setup, like NHS in the UK, or through employer funded health insurance backed with public aid for people in catastrophic situations like in the US? Either way the amount of money spent could be used for better purposes if a "one time" payment, even a large one, for a cure were made, I think?

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Permalink Reply by Nicole on January 29, 2012 at 2:05pm

For the sake of my own sanity, I sure hope so.

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Permalink Reply by Abyssinian1 on January 29, 2012 at 8:17pm

Unfortunately, Dr. Faustman's research is in need of funding to finish the Phase 2 trials. They only have funding for one year of the trials, which isn't enough for the FDA. Because the drug she's using is generic, there's no reason for any pharmaceutical company to fund her - no patent = no way to squeeze every last dollar out of the pockets of the Type 1 community in exchange for an expensive 'cure'. Hence, she's having to rely on donations, which isn't the most steady source of income. The JDRF has repeatedly refused to fund her research, instead funneling money to the developers of the 'artificial pancreas' (read: something pharmaceutical companies can charge diabetics and their insurers for wads 'o cash until they die).

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Permalink Reply by Ancy on January 30, 2012 at 2:39am

Hi..
I also think there wont b any cure for it...but still on positive note u neva know....

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Permalink Reply by Brunetta on January 30, 2012 at 3:35am

This discussion has become most fascinating and informative. As many of you already know, I am a perpetual optimist and donate blood yearly to the Faustman Lab. So I will reiterate my previous answers.. Of course, YES;and in my already 57-years-old lifetime. Yes the "cure"r will have to be complex and individualized as the autoimmune attack is complex and individualized..but it can be accomplished.

I agree that Dr. Faustman and other researchers desperately need funding for a cure NOW..Could millionaire ( or close to those type of $$$)type ones with a high-profile ( ex:Jay Cutler, Noah Jonas,Brett Michaels ) be motivated through a letter -writing campaign to contribute to her research? Just a thought . It would do wonders for the cause and shed nothing but positive light on the Tyoe One Celebs.. They get more requests for ad endorsements and more money, too.
Have a great day, all!!

God bless,
Brunetta

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Permalink Reply by Stacey on January 30, 2012 at 11:16am

Nope.

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