Replies to This Discussion

Permalink Reply by mary on February 27, 2012 at 3:13pm

Will she be looking at those of us with LADA? Will we be able to participate in the studies? Will the vaccine work on us?

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Permalink Reply by Gary on February 27, 2012 at 4:01pm

I'd like to know if the treatment proves unsuccessful can I have all my donation money back? All kidding aside, my main question is being I am nearing forty years with diabetes do you feel its crucial for me to be involved with the treatment in the near future for it to have a chance to work for me or it likely wouldn't make a difference at this point anyway?

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Permalink Reply by Manny Hernandez on February 27, 2012 at 4:02pm

Two great questions. Keep 'em coming!

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Permalink Reply by Paul Patten on February 27, 2012 at 4:32pm

I have two questions.
1) Are there type 1's who are C-peptide negative even with the more sensitive test?
2)Will BCG work in diabetics who have insulin antibodies only?

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Permalink Reply by Manny Hernandez on February 27, 2012 at 5:06pm

Good ones.

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Permalink Reply by Kathy on February 27, 2012 at 4:34pm

I haven't seen much data from her studies. I'd like to know the difference in C-peptide pre and post-treatment.

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Permalink Reply by Manny Hernandez on February 27, 2012 at 5:06pm

Fair enough! Another great question.

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Permalink Reply by Bernard on February 27, 2012 at 5:15pm

One of my questions is that same as @Gary, as I'll have had type 1 for 40 years this coming September.

I know they're starting work on Phase 2 trials. Has she an estimate for how long it will take to complete those, and how long after that before we see the results? I'm guessing it will be around 2015 for the results, but I'm hoping it's before then.

Besides fund-raising is there anything else we can do to help move this research forward?

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Permalink Reply by Manny Hernandez on February 28, 2012 at 10:22am

Thanks, Bernard! I was thinking of asking her that (about ways to help her) too. :)

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Permalink Reply by Tony on February 27, 2012 at 5:46pm

Would the treatment help with other autoimmune diseases?

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Permalink Reply by samsmom on February 29, 2012 at 1:10pm

I wonder about this one too. My daughter has T1, Hashimoto's & vitiligo. She participated in the Defend 2 trial for otelixizumab, which tried to extend the honeymoon period. The trial doc said if it worked, it might also help the thyroid. So would this have the same potential?

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Permalink Reply by gigem99 on February 29, 2012 at 2:22pm

I asked Dr. Faustman's assistant Nick about this. My daughter was recently dx'd with Grave's disease - like Hashimoto's, except hyperthyroidism instead of hypothyroidism like Hashimoto's.

Both diseases are autoimmune in nature, and Nick replied that they were specifically targeting both those conditions. I'm sure it will be a different protocol, but they should gain a lot of good info from this intitial trial with the BCG.

Tom

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