I was originally diagnosed gestational (she's almost 18 now) and put immediately on insulin. I then failed the follow-up test so went on a pump for the next 6 years (and 2 more pregnancies, both from metformin). After the last, I lost some weight and got too sensitive so dropped the pump. I then tried several meds that didn't work and eventually tried the pump again for a year. I found out about functional medicine, which drastically reduced inflammation once I healed my gut, dropped the pump again. My previous endo tested for GAD and ICA 3-4 years ago, both negative. He suggested MODY, but 2 genetic tests proved negative. I also have PCOS (diagnosed at 17, low BMI), but cycles have become normal, although there could be some lingering insulin resistance, maybe?
I do have Hashimotos and am C/T for DQ8, which is associated with type-1. I just had my new integrative med family doctor test for GAD, ICA, ZnT8, all negative. IA-2 is 1.5H (<0.8 (U/mL)) and Insulin AutoAntibody is 42.3H (<0.4 (U/mL)). Could these confirm LADA? I have not used insulin for ~5 years, so could the IAA be from previous usage, or am I actually producing antibodies to my own?
A1C has been consistent 6.1-6.4 for the past several years, fasting is now ~135-140, rarely go above 300 and it drops quickly once it gets high, so I know I am still producing insulin. Non-fasting after small low carb breakfast C-Peptide (0.80-3.85 (ng/mL)) is 1.60, which looks to be lowish.
I have done what I can with diet and exercise (mostly AIP), so I know I need to work on getting some sort of treatment, especially since MODY2 wasn't found. Meds, including metformin, had negligible effect on A1C and FBG, so insulin is likely going to be it again.
I feel I am a lot closer to finally identifying my diabetes and dropping the type-2 label (normal/low BMI, not type-2 phenotype), but don't know if I am there yet.