Lantus looses its effectiveness after 28 Days after OPENING.
So, once OPENED it has a useable life of 28 days..PERIOD. Using beyond 28 days can lead to PROBLEMS with BS levels. Does not matter storage condition or vial/pen, remember the key word is "OPEN". Once the seal is violated, even if you do not use a single unit of the Lantu it is still spoiled after 28 days....
Ok OK! ... I will TRY and explain the problem, but it can get a bit complicated, ie harder than READING the drug info sheet that comes with EVERY Rx of Lantus.
The 28 days is stated clearly with every vial/cartridge/pen of Lantus, Does anyone bother reading the info sheets that come with Lantus, Humalog and/or ALL their other Rxs?
The HUMAN element....... Every diabetic is different. Some have some reserve natural insulin/beta cell capacity (some DO NOT) . IF you are one of these LUCKY diabetics, then a slight decline in Lantus potency may have less of an immediate effect. Your beta cells may have recouperated some durring the time the Lantus was a full strength. In THAT case you MAY be able to use a vial (etc) Lantus an extra day or even a couple days beyond the 28 days. USING Lantus BEYOND 28 DAYS for many can be RISKY, even life threatening!
For most type-1s, you can get into TROUBLE very quickly and risk possable DKA. Using an OPEN container of Lantus beyond 28 days can lead to not only complications, DKA or even a very expensive ER visit or hospitalization! Very few type-1s have ANY reserve beta cell function to compensate for the weakening Lantus. Some that do have a little reserve, some may be able to get an extra day, others may get 2 or even 3 extra days.
For ME. I noticed via my glucometer logs a trend/change when I try using a vial past the 28 day mark. There are time I hae a little LIMITED natural beta cell capacity, and there are time I have NOTHING.
I have tried, with some success adjusting my Lantus dose to compensate. I usually get away with it, BUT, I DO NOT RECOMEND THIS TO ANYONE!
Bottom line. use your Lantus past the 29 day mark AT YOUR OWN RISK!
Does this HELP anyone here understand the situation and WHY one person can seemingly get away with it and another diabetic CAN NOT? I said seemingly because doing this is RISKY and the piper may collect on this at a later date down the line.