I'd like start a resource page for Monogenic Diabetes. As a start, I'll include key links below.
Diabetes Genes - A site run by Prof AJ Hattersley's group at Exeter, UK, perhaps the worlds foremost authority on this subject
Monogenic Diabetes - A site run by Kovler Diabetes Center at University of Chicago, the leading center in the US.
National Diabetes Information Clearinghouse (NDIC) - A site funded by NIH providing basic information on MODY
Please feel free to add resources, I'll try to combine all of them into the main list.
Here are 3 documents that give great overviews of MODY research knowledge.
- Geneva Children's Hospital Pediatric Endocrinologist's Powerpoint Presentation I found on the web.
- Article by Dr. Stefan Fajans, U. of Michigan Head of Endocrinology, New England Journal of Medicine article, 2001
- Article by Dr. Stefan Fajans, U. of Michigan Head of Endocrinology, Diabetes Care Journal, August 2011 summary of knowledge about MODY and implications - VERY helpful.
Thank you for the information, those aren't things that I had seen before.
I've got a number of links that I have bookmarked at home... will need to gather them together and post.
These were some of the bookmarks that I had on my home PC about MODY:
Some overview information about MODY:
Specific MODY-1 Overview:
A presentation with some more details about MODY:
(Looks to be the same as one that April Posted)
I forgot to mention one of the other resources that I had stumbled upon:
Frontiers in Diabetes Vol. 15
Molecular Pathogenesis of MODYs
Franz M. Matschinsky,MD
Department of Biochemistry and Biophysics and
Diabetes Research Center, University of Pennsylvania
Medical Center, Philadelphia, Pa., USA
Mark A. Magnuson, MD
Department of Molecular Physiology and Biophysics
Vanderbilt University School of Medicine
Nashville, Tenn., USA
It is available through Amazon:
I read it early on, but haven't gone back now that I know for certain that I'm dealing with HNF-4a
These are great resources. When I get a chance, I'll compile them at the top.
Hello BSC and Knightshade:
I, too, continue to build my knowledge base about MODY diabetes.
It is my privilege to have had the privilege to have spoken personally with Dr. Stefan Fajans, whose research summaries have been uploaded here by several of us. He is a brilliant man - without whom we would not have the basic understanding of our disease.
He just celebrated his 94 birthday and he is still sharp as a tack - we should all be so lucky!!!
If you would like to wish him a Happy Birthday or thank him for his scientific contributions over the past 50 years, you may send him an in care of his assistant, Sheri Amici, at University of Michigan Medical School: firstname.lastname@example.org (he is, of course, "emeritus" or retired from his position as head of the endocrinology department at the medical school there. . . but Sheri still acts as a part-time assistant and can forward email to Dr. Fajans).
Please understand that Dr. Fajans no longer practices medicine - so writing to Ms. Amici can't help obtain testing or a diagnosis -- Kovler is the best bet for that. But he was the pioneer in the MODY area of diabetes and is revered by all who continue to research the genes that cause MODY. Happy Birthday, Dr. Fajans and Kudos!
In the meantime, I am uploading several more files for the MODY reference library.
Best to all,
There was a good overview article in the British Medical Journal in October:
I use this one to point doctors at when I meet one that hasn't heard of MODY (which happens quite a lot!).