Hi Everyone,
My husband and I are getting ready to start another round of IVF. After the last attempt failed, we switched doctors. Our new doctor ran a very specific test for me because of a miscarriage in 2011 and poor egg quality for the IVF cycle. The test revealed that I have a MTHFR gene mutation and this may have caused the previous pregnancy issues. In order to start a new round of IVF,the treatment for this gene mutation is taking heparin injections twice daily in the seven days before implantation. The injections are 5,000 units each. Has anyone else heard of this or had to take heparin when trying to get pregnant? I have to admit that hearing that I have to take a drug that is used for dialysis patients freaked my healthy diabetic mind out! Any feedback on this would be great!! Thanks!

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Not sure how it affects diabetics, but my cousin also has MTHFR (I only have one of the two mutated genes so I don't have to take heparin injections). She had trouble staying pregnant and it wasn't discovered until she had a stillborn in 2007 that it was because of the MTHFR. She now has two healthy children that she carried to term taking the heparin shots. She never had any trouble health wise taking the shots, that I know of.

Did your cousin have to take heparin throughout her pregnancy or just in the beginning?

She took blood thinning shots up until a couple of weeks before her inductions. I'm not sure if they were heparin, but I will find out.

Lovonox (I may have the spelling wrong on that). My sister also took them during her second pregnancy due to a protein s deficiency. She said they hurt going in, but there were no side effects and the pain wore off pretty quickly.

Thanks Anna! I saw my doctor today and felt much better informed when asking him questions about this! My best friend is a dialysis nurse and she said to not eat certain types of food, particularly with vitamin k. She mentioned leafy green veggies, egg yolks, canola oil and green apples. Was your cousin given any diet restrictions?

Not that I know of, but it's possible.

I got tested for this gene in my early pregnancy as my sister has it and she had a miscarriage and a premature baby

My Drs said if I had the gene they would recommend increasing my folate doses
Might be worth discussing. I however was found to be only a carrier rather than having it. Apparently 45 percent of the population have it, which I was surprised about

Good luck, hope it works out for you





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