I've been periodically posting on here about my experiment with Symlin. I decided this morning it is a failed experiment. My main goal for using Symlin was weight loss. I was at a perfect weight for me after my diagnosis (I lost 40 pounds to get there!) and then slowly but surely have gained 10 pounds in the two years I've been on insulin. I'm still at an ok weight, but didn't want to gain anymore, and at my age (62) it's very hard to lose.
So my experience with Symlin: It took me awhile to figure out dosing and we all seem to be different. What I finally hit on is doing the Symlin about 15 minutes before eating so I could experience the fullness, then doing my insulin an hour after eating. I then did my post-prandial check at the 4 hour mark instead of the usual 2 as that is when my peaks seemed to hit with Symlin. I had been able to cut my breakfast and lunch insulin in half and for dinner I took 60% of what I formerly used. My numbers were also somewhat more stable than before I started Symlin so in that sense my experiment was a success. However that wasn't my main reason for using Symlin and my numbers weren't bad before.
I wasn't losing any weight, just up and down the same two pound variation like before. I thought maybe I needed a higher dose than the 60mcg recommended for Type 1's so I slowly increased it to 120. My blood sugars became even more stable, but still no weight loss.
I was going to finish what I have on hand (about 2 weeks) but decided not to bother. I was on Symlin for 3/12 months and the 120mcg dose for over a month, so I figured that's trial enough. If I start to gain again I might freak out and consider starting again..lol but meanwhile I'm going to continue eating the reduced servings I have been and try and reduce a tad more and increase exercise. Oh well, I gave it a try!