Quick question for everyone that I can't seem to find the answer to, maybe my info hunting skills need an upgrade...but... Is a unit of insulin a unit of insulin? Meaning....All things being equal,…Continue
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"I was thinking about what you said about eating and not needing as much or no insulin. Usually when I am sick my sugar is really high but the times I have had infections and taken anitbotics my sugar is so much easier to control, I almost wonder how…"
"NO!! A unit of insulin is measured by its weight when it's in crystaline form, not by how much it lowers blood sugar in any sort of animal or person. It is totally possible that your body metabolizes one insulin so that it does more per unit…"
"So glad you got the info you wanted, Uproden! It's so interesting at times that on this board we have "scientific thinkers" (of which you appear to be one), philosophical thinkers, practical/logical thinkers, spiritual thinkers,…"
"A unit is a unit by volume - is only true when you are comparing insulins that are the same 'potency', such as U-100, which is the case with most insulins in US today.
U-100 was formulated so that it is always 100 units / ml.I think U-40…"
"That is true, I don't think they use the rabbit method regularly anymore, but the base definition of the chemical assay method was done to be compatible with the original definition of the HYPO RABBITS."
"This is from the 1960s, there has been some significant progress in the last 50 years. Today we have moved to performing chemical assays of insulin and I don't believe the hypo rabbits are used much anymore."
"Kiva's explanation explains the long acting versions perfectly and in detail..
A unit is a unit is a unit. Long acting and short acting insulins both have, ultimately, the same job in the body. Long acting insulins act longer because they…"
"Another review article on measuring insulin potency and defining the unit, this one from 1960. They show more ways of measuring insulin potency, still using the effect on a rabbit as the definition: Methods of Insulin Assay
"The answer lies with Megaminx's reply up above.
While there are relatively slightly different structural difference between the insulin molecules of one type and another they are also sufficiently the same so that one insulin for all practible…"
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