I'm not really sure. "Anti" would seem to suggest that it opposes something. Doctors love the analogy of an anti-body taking residence in order to "fight" a virus or some other bad guy.

Oh Kay.

So the anti-GAD antibody is fighting GAD? GAD is an enzyme helpful to GABA. GABA is a neurotransmitter that is also an inhibitor to other neurotransmitters like serotonin, dopamine and norepinephrine. GABA is THE inhibitory neurotransmitter on the job. So, anti-GAD kicks the pawns, the GAD enzymes, that defend and create the powerful GABA, thus lowering the amount of GABA in your noggin (and spinal fluid).

wot. Sounds like a sci-fi novel.

What's an enzyme? I can buy some at the health food store. I've even seen GABA in a bottle. (Just a friendly reminder that most health supplements are garbage.)

I take GABA in a bottle, in this wonder drug called diazepam (valium). GABA is also found in alcohol.

So, this is what I know or think I know.

From Googling:

If you don't have enough GABA, you can get Stiff Person Syndrome, diabetes, manic-depression, ADHD, PTSD and the list goes on. I'll mention anxiety attacks below.

OT: I list these psychiatric diseases b/c after years and years, I still can't get a diagnosis re: my "mood disorder."

From experience:

Booze lowers your inhibitions (fight or flight, ref. norepinephrine?), makes you depressed (serotonin?) and makes you lethargic/creates muscle weakness (dopamine, eh?).

That sound right. [corrections appreciated]

I take valium. It relaxes my muscles and calms the startle reflex. It doesn't make me sleepy, tho. And it doesn't make me drunk or high. Through almost 9 years of experience with this drug, I've seen how powerful it is on other people. Do not try it - very addictive to the normal human. I'm not normal, evidently. (Not special either. Some people have anxiety attacks and take a similar GABA-ergic! drug called Xanax and don't get "addicted.") I love the word Gaba-ergic. Someone ought to give scientists a good thesaurus. Stiff Man Syndrome is an honored member in The Hall of Ridiculous Disease Names. It not even a "syndrome". How 'bout a dictionary?

Insulin is a very direct, pass "go" metabolizing tool. They began using insulin before they figured out what GABA did to little baby rodents. It simply ignores your lack of GAD and GABA and goes right into the fray to fight off those bad sugars.

Booze and vinegar also lower blood sugar. How does that work?

Do we go to the health-food store and buy lots of GAD enzymes to help lower our blood sugar and keep us sane?

Or do we continue using the big guns to fight/out-flank this antibody, anti-GAD? Right now, I'm sticking with the big guns.

Views: 22

Comment by snowangel66 on May 29, 2009 at 3:06pm
HAHAHA brilliant


You need to be a member of Diabetes community by Diabetes Hands Foundation: TuDiabetes to add comments!

Join Diabetes community by Diabetes Hands Foundation: TuDiabetes



From the Diabetes Hands Foundation blog...

DHF receives $200,000 grant from Novo Nordisk

Grant given to support programs aimed at bringing together people touched by diabetes for positive change BERKELEY, CA: December 4, 2014 – Diabetes Hands Foundation (DHF) has received a grant of US$200,000 from Novo Nordisk to support programs aimed at Read on! →

Guest Post: World Diabetes Day 2014 on Twitter… sifting through the data

At Symplur we track hashtags, keywords, user accounts, and pretty much anything else on Twitter that has to do with healthcare. We collect the data and then build countless ways to slice it up so that we’re able to better Read on! →

Diabetes Hands Foundation Team


Manny Hernandez
(Co-Founder, Editor, has LADA)

Emily Coles
(Head of Communities, has type 1)

Mila Ferrer
(EsTuDiabetes Community Manager, mother of a child with type 1)

Mike Lawson
(Head of Experience, has type 1)

Corinna Cornejo
(Development Manager, has type 2)

Desiree Johnson  (Administrative and Programs Assistant, has type 1)


Lead Administrator

Brian (bsc) (has type 2)


Lorraine (mother of type 1)
Marie B (has type 1)

DanP (has Type 1)

Gary (has type 2)

David (has type 2)


LIKE us on Facebook

Spread the word


This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information: verify here.

© 2014   A community of people touched by diabetes, run by the Diabetes Hands Foundation.

Badges  |  Contact Us  |  Terms of Service