So I am now looking into the fact (or myth) that Lyrica causes people to gain a significant amount of weight. Since taking it myself I have noticed a increase in my weight which I don't need. I lost about 50 pounds two years ago and have managed to keep it off until this Lyrica came along. Bummer huh? I just added Cymbalta to help with my neuropathy pain and the depression I am experiencing along with it. Only on day two of the Cymbalta so I don't have anything to say about that as of yet. Just curious what your Lyrica story is.... I am taking 100mg in the AM and 100mg at dinner.