High blood glucose reaction to Tylenol #3 with codeine/caffeine

Hi! I just had surgery and was given Tylenol #3 with codeine/caffeine for pain meds ... have had hi's all night ... changed out my pump set and insulin to a fresh vial but still battling hi's?? Has anyone reacted to this drug this way? Am going to discontinue it, maybe replace with Ibuprofin/Advil and see if there is a difference. Thanks.

Tags: Medication, Pain, Reaction

Views: 1166

Reply to This

Replies to This Discussion

Surgery is a huge stress and stress can cause BGs to sky rocket. In addition some diabetics have noted that caffeine (coffee) causes a spike in BGs presumably by causing the release of adrenaline. It sounds like a tough situation. I would suggest that you signifigantly up your basals via a temp basal. It is tough to guess how much you should increase your basals. 50% increase or 100% increase is not out of the question. Good luck

Pain is a stress and can certainly result in high blood sugars. Also, injury (like surgery) results in inflammations that again can result in high blood sugars. Acetaminophen can interfere with blood sugar tests, but it usually causes false low readings and it is not a strong effect. I've not heard of codeine affecting blood sugars or test results. You could try Ibuprofen and see if there is a change, but it may just be that your body has reacted to the surgery with high blood sugars.

ive taken tylenol with codeine to sleep a coupe of nights and have always woke up high the next a.m. hope youre feeling better after surgery.

I think it's the surgery doing it. I had to battle high BS's after nasal surgery.




From the Diabetes Hands Foundation blog...

Diabetes Among Hispanics: We’re not all the same

US Hispanics are often portrayed in the press as a single, monolithic group. But anyone who has spent any time in San Francisco’s Mission District or the Bronx can tell you, we’re not all the same. Now we’re finding out Read on! →

Diabetes entre los hispanos: no somos todos iguales

Traducido por Mila Ferrer.    A menudo los Hispanos en Estados Unidos son retratados en la prensa como un solo grupo, monolítico. Pero cualquiera que haya pasado algún tiempo en el  Mission District de San Francisco o el Bronx se Read on! →

Diabetes Hands Foundation Team


Manny Hernandez
(Co-Founder, Editor, has LADA)

Emily Coles
(Head of Communities, has type 1)

Mila Ferrer
(EsTuDiabetes Community Manager, mother of a child with type 1)

Mike Lawson
(Head of Experience, has type 1)

Corinna Cornejo
(Development Manager, has type 2)

Desiree Johnson  (Administrative and Programs Assistant, has type 1)


Lead Administrator

Bradford (has type 1)


Lorraine (mother of type 1)
Marie B (has type 1)

Brian (bsc) (has type 2)

Gary (has type 2)

David (dns) (type 2)


LIKE us on Facebook

Spread the word


This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information: verify here.

© 2014   A community of people touched by diabetes, run by the Diabetes Hands Foundation.

Badges  |  Contact Us  |  Terms of Service